2016年4月19日星期二

Testing Methods of Polycystic Kidney Disease (PKD) Patients

People who have a family history of Polycystic Kidney Disease are suggested to have related examinations regularly in order to test out this disease as early as possible. An early diagnosis has a significant role in the treating this disease and getting a good effect. However, which kind of examination is available? Here is a general introduction as follows:

Routine urine test: no abnormality can be found in early stage, and microscopic Haematuria can be found in middle and late stage. Some patients may have protein in urine. White Blood Cells and pyocyte can be found when there is complicated by Stones and Infections.

Body Check: unilateral or bilateral kidneys can be touched in nodule shape through body check. Pressing pain can be felt when there is a infection. 50% patients have increased size of waist.

Urine osmotic pressure test: even in the early stage when there is only very few cysts, expressions of renal concentrating function damage can be observed. This means that this damage may not be related with kidney structure damage only.
Instead, it may also be related with renal insensitivity to antidiuretic hormone. Renal concentrating function decline happens before glomerular filtrating function decline.

Serum creatinine is increasing progressively with kidney compensatory ability decline. Creatinine clearance rate is a more sensitive index.

In KUB plain film, increased kidney image can be seen with irregular shape.
Through IVP, deformation tendency of compressed renal pelvis and renal calices can be found. Renal pelvis and renal calices can be found in strange spiderlike shape. Renal pelvis is plain and wide, while renal calices neck become longer and thinner, showing a curved shape.

Through Type-B Ultrasonic examination, a large number of shadows can be found in bilateral kidney region.

Bilateral kidney enlargement can be found in CT examination, with lobulated shape. Many cysts with thin cyst wall can be found inside fluid.


Since Polycystic Kidney Disease is a kind of genetic disease, people who have Polycystic Kidney Disease patients in their family should have a high cautious on their body health. If they can have regular body check, this disease can be tested out in the early stage, which is greatly helpful for patients to get a good effect, playing a very important role in helping patients avoid dialysis in the future.

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