Lupus nephritis is a kidney disorder caused by systemic lupus erythematosus which is an autoimmune disease, involving many organs of the body such as kidneys, heart, brain etc.
How lupus happens?
Healthy immune system produces antibodies to fight against foreign matters such as virus, bacteria or other infections so as to keep people healthy. However, people with lupus often have an abnormal immune system, meaning the antibodies can’t tell foreign substances from one’s own healthy cells, tissues and organs. Consequently, those antibodies attack its own body parts resulting in the occurrence of SLE.
Routine tests for lupus nephritis include biochemistry tests, blood test, urine test, virus examination and series of coagulation.
Immune special tests are tests for autoantibody, alexin series and special tests for uremia.
Tests for Autoantibody
The tests of autoantibody aim at diagnosing if the patients have lupus or not, to tell its severity and to recommend clinical medications etc.
Alexin Series Examination
The tests of alexin help make sure its degree in patients’ body. It is the sign of lupus. The alexin includes C3, C4, CH50, Clq and B factor. The reduction of C3, C4, CH50 and C1q signals the activation of classical alexin pathway, while decreased C3 and B factor indicates an alternative pathway is activated.
Above these is about the cause of lupus nephritis and detection methods, all introduced in this area if you have other questions, you can click the following article online teacher consultation, or to organize your case is sent to the kidney-support@hotmail.com inside this email, we will give you a professional guidance.