Newest Treatment of Hepatitis B Virus (HBV)-associated Nephropathy

Hepatitis B Virus (HBV)-associated Nephropathy refers to the inflammation of glomeruli caused by HBV. Left untreated, it may develop into Chronic Kidney Failure. Therefore, it is essential for the patients with HBV-associated Nephropathy to receive treatment as early as possible.

Immunological injury plays the major role in HBV-associated Nephropathy. When HBV invades into body, they can not be killed by the related antibodies. As a result, when HBV antigens encounter antibodies, they will bind to each other to form immune complexes in blood. These immune complexes can not dissolved in blood. Afterwards, they will enter into glomeruli and cause inflammation of glomeruli. The inflammation will damage the epithelial cells of the glomerular capillaries resulting in HBV-associated Nephropathy. As the barrier function of glomerular epithelial cells is impaired, they can not prevent the leakage of protein, red blood cells. In clinic, the patients will present proteinuria, hematuria and high blood pressure etc.

The patients with HBV-associated Nephropathy usually are not sensitive to hormone. After a long term of hormonetherapy, most of the patients develop Chronic Renal Insufficiency. In order to achieve a favorable therapeutic effect of HBV-associated Nephropathy, immunotherapy is introduced into the field of kidney disease treatment.

Immunotherapy aims at reliving the symptoms of HBV-associated Nephropathy by correcting immune disorder, removing immune complexes as well as restoring the impaired kidney structure.

In immunotherapy, blood purification can remove the pathological factors and block the immune complexes formation. Moreover, Micro-Chinese Medicine Osmotherapy not only can degrade the immune complexes and promote their excretion out of body, but also can correct the immunity and promote the clearance ability of the body’s own. Therefore, these treatment methods can stop the disease aggravation effectively.