2016年6月10日星期五

Hypertension and Polycystic Kidney Disease

Many Polycystic Kidney Disease patients have hypertension at the same time. But why patients have hypertension, though this is very common among Polycystic Kidney Disease patients. Actually, hypertension caused by Polycystic Kidney Disease, which is a kind of secondary hypertension, is more harmful to our body. We should learn more about it.

The reason why Polycystic Kidney Disease patients have hypertension can be described as followed: cyst enlargement can produce pressure on normal kidney tissue and blood vessels in kidney. This can cause ischemia to kidney tissue and blood vessel, resulting in blood flow decrease in local part. Once receptor of kidney feels this change, it will give a sign of secreting more rennin, which can increase the concentration of angiotensin and cause vasoconstriction, thus blood pressure increasing. It is a vicious circle between hypertension and kidney damage. For this reason, Polycystic Kidney Disease patients should pay high attention on hypertension and try to control blood pressure in normal range.


The occurrence of hypertension is a sign of disease aggravation. More than 50% patients will get hypertension before serum creatinine increasing. Once hypertension occurs, arterial vessels will shrink which may induce injury to the wall of blood vessel. Under such condition, cholesterol and other materials can deposit on blood vessel wall easily, thus thickening and hardening blood vessel wall. Besides, this may also involve to renal artery and glomerulus, resulting in kidney ischemia, glomerular atrophy and small artery fibrosis. With this happening, this disease may develop into end stage renal failure gradually. If you need more information about this, you can email to kidney-treatment@hotmail.com or consult our doctors online for free.

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