Clinically, most of Polycystic Kidney Disease patients have family history and it happens more to male than female. Generally Polycystic Kidney Disease has no symptoms in the early stage and the symptoms often appear when patients are 30 to 40 years. Some common symptoms of Polycystic Kidney Disease can be listed as followed:
Ⅰ.The enlargement of the kidney. With cysts growing and increasing, besides
producing pressure on surrounding kidney tissue, they will also cause kidney
Ⅱ.Discomforts in waist and abdomen. The increase of renal capsular tension or
the pull of renal pedicle vessels and nerves can lead to dull pain. If there is
bleeding in the cyst and the blood clot block the urethra or there is infection
in the cyst, the pain will be acute suddenly and even cause renal colic.
Ⅲ. Hematuria: If the vessels are broken due to the pull, there will be gross
Ⅳ. Proteinuria and leucocyturia: Urine protein is generally lower than
1g/24hours. Leucocyturia is commonly seen, which doesn’t suggest infection.
Ⅴ. Hypertension: It is commonly seen and will directly influence the
prognosis of the disease. It is related to the pressing of the cyst on normal
renal tissues and causes renal ischemia and water and sodium retention.
Ⅵ. Damage to renal function: The loss of renal function is related to the
pressing of the cyst and is also relevant to other tissues that have ischemia,
sclerosis, inflammation, fibrosis and the high filtration and high perfusion of
the remaining renal tissues.
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