Indication and Contraindication of Renal Biopsy

Renal biopsy is an important exam in diagnosis of Kidney Disease. It has very important guidance meanings for the treatment and predicting the disease prognosis. Therefore, it is essential for the patients with Kidney Disease to learn the indications and contradiction of renal biopsy.

Indications of renal biopsy 

1. Primary Kidney Disease

A: Acute Nephritic Syndrome

When the renal function aggravates sharply or the patients are suspected to have Acute Nephritic Syndrome, the patients should take renal biopsy at once.

B: Primary Nephrotic Syndrome

It is essential for the patients with Primary Nephrotic Syndrome to take renal biopsy. It can help them figure out the pathological types to guide its treatment.

C: Asymptomatic hematuria

The patients have asymptomatic hematuria, but can not get a definite clinical diagnosis. It is essential for the patients to take renal biopsy.

D: Asymptomatic proteinuria

Asymptomatic proteinuria lasts for one day, but the clinical exams can not give a clear diagnosis of the abnormal symptom.

2. Secondary or genetic Kidney Disease

In clinic, if the patients are suspected to have Kidney Disease, renal biopsy can help them get a confirmed diagnosis of the disease. In some cases, for the patients with confirmed diagnosis of Kidney Disease, renal biopsy has great significance in guiding treatment and predicting prognosis.

3. Acute Renal Failure

Clinical or lab exams can not give a confirmed diagnosis of the disease cause. In this case, the patients should take renal biopsy at once.

4. Transplanted kidneys

For the patients with transplanted kidneys, if their renal function declines for no clear reasons or they experience serious kidney rejection or are suspected to have the reoccurrence of the primary disease. The patients should have renal biopsy at once.

Contradictions of renal biopsy

Renal biopsy has enormous trauma to the patients. After the check, it is very prone to lead to bleeding, infection and other complications. Therefore, it is essential for the patients to know the contradictions of renal biopsy.

1. The absolute contradictions of renal biopsy

A: The patients have bleeding tendency.

B: Serious high blood pressure.

C: Solitary kidney

D: End stage contractedkidney

2. Relative contradictions of renal biopsy

A: Renal tumor or aneurysm of the renal artery

B: Polycystic Kidney Disease (PKD) or enlarged kidneys

C: Chronic Renal Failure

D: Obesity

G: Serious ascetic fluid

H: Active pyelonephritis, nephrotuberculosis, hydronephrosis or nephrapostasis

If the above conditions do not accord with your conditions, you can consult us on line to know if you can take renal biopsy.

More: Indications of Renal Biopsy for Nephrotic Syndrome