Immunotherapy for Autoimmune Kidney Disease

In Kidney Disease, more than 95% of them are caused by the immune disorder or abnormality. Immune-mediated Kidney Disease accounts for approximately 20~30% of the cases of End Stage Renal Failure. The current therapy for Autoimmune Kidney Disease is mainly the combination of hormone and immunosuppressive drugs. However, the tremendous side effects can increase the mortality and also can not prevent the relapse of the disease. With the deeper understanding of the immunopathogenesis, a more effective and better-targeted therapy: immunotherapy is introduced into the treatment of Autoimmune Kidney Disease.

In normal case, the immune system prevents the foreign pathological substances from invading into our body. Therefore, our body can keep healthy and well. However, in some cases, the immune system is disordered so it can function normally. When the foreign pathological substances invade into body, the activated antibodies fail to defeat them. On the contrary, the antigens will deposit in glomeruli or bind with the antigens in glomeruli in situ to form immune complexes. The body will does its best to clear up the immune complexes thus leading to immune inflammatory response. When the immune inflammatory response occurs excessively, it is called hypersensitive reaction. It not only can not remove the immune complexes, but also do much harm to renal tissues and cells.

Therefore, to treat Autoimmune Kidney Disease, restraining hypersensitive reaction and clearing up immune complexes are two important processes in immunotherapy.

Firstly, by applying a series of low-side effects of hormones and immunosuppressive drugs, the hypersensitive reaction can be inhibited temporarily. It can stop the further damage to renal tissues and cells.
Secondly, the immune complexes are the inducement of hypersensitive reaction. On one hand, Chinese herb medicine can degrade the immune complexes and then the degraded immune complexes will be discharged out of body by systemic circulation. On the other hand, the Chinese medicine can improve the immunity and improve the body’s clearance ability.

Third, as the immune inflammatory response has damaged the renal tissues and cells. For the multi-differentiation and regeneration abilities of Immunotherapy, Immunotherapy plays the major role in restoring the kidney function.

Immunotherapy treats Autoimmune Kidney Disease from the pathogenesis so it can treat the disease fundamentally.

If you are Kidney Disease suffer and do not know much about this new therapy, you can consult us on line. We will do our best to help you.