Why do you have (PKD)?
The typical feature of this disease is family gathered tendency. Who have this disease among your parents or brothers and sisters? (If not checked, you can ask whether they often appear waist sour and bloat.) As long as one of your parents has Polycystic Kidney Disease (PKD), the rate of getting this disease for every child is 50%. (If checked that it is not this kind of disease, there is no need to worry about. Because it will not develop into the disease.)
How can people have Polycystic Kidney Disease (PKD)? It’s a hereditary disease, which is autosomal dominant inheritance and develops progressively. Most patients get morbidity on adult period while a part of patients may get morbidity accompanied with liver cyst and stone. The notable feature is that tubular epithelial cell proliferates abnormally. When tubular epithelial phenotype transforms into cyst epithelial cell, secretion occurs and fluid secretion grows gradually.
But there is no normal secretion ways. With the growth of age, quantity of Sac liquid accumulates, cyst increases in size, Sac pressure, cyst surface tensions increase. At the same time, some sensitive patients feel waist uncomfortable, sour and bloated. While cyst has segmental infections, pains will occur. With cyst increases gradually, kidney normal structure will be replaced by cyst. It occurs to have gradual decreases of glomerulus barrier function, tubular concentration, reabsorption and regulating functions. Clinically, it can be found to have high blood pressure, routine urine and abnormal kidney function.