If some of your symptoms conform the usual symptom of FSGS (focal segmental glomerulosclerosis), your doctor will review your medical history and arrange lab tests to assess kidney function and also estimate which part is destroyed by renal inflammation. The usual tests are:
Biopsy was considered as the most accurate test to confirm the diagnosis of many kidney diseases. Doctors only can give you the diagnosis of FSGS through biopsy. However, it will give a great hurt for people and they often have pain in the part of biopsy when the weather is not well. So in our hospital, some other tests can replace the biopsy. Through some urine and blood tests, physician can give you a suitable treatment for you to remove FSGS.
Blood tests for toxic substances in the blood
BUN (blood urea nitrogen), CR (creatinine) and UA (uric acid) is the
traditional indexes to estimate how well the kidneys are working. However, they
are all the late indexes that only can indicate kidney function in serious stage
of kidney disease. Even if some people are in FSGS and more than 50% of kidney
tissues are affected, their BUN, CR and UA may keep well in that period and
people are easy to ignore the treatment for FSGS.
Cyc C is another end product during metabolism, and test of Cyc C is an early
index to tell the kidney function. As long as kidney tissues has a slight hurt
from renal inflammation, the level of Cyc C is increased to alert people to have
Urine tests for kidney damage
U-malb is one of sensitive indexes to detect the damage in glomeruli. If the
microalbumin is fund in urine and the count is more than 30mg/L, their glomeruli
which are the main tissues of filtration are hurt.
UNAG or UGGT is used to tell how well the renal tubule is working. The main
filtering work is done in the nephrons which are combined by glomeruli and renal
tubules. If the renal tubules are damaged, they also cannot function well.