2016年10月15日星期六

Main Causes of Polycystic Kidney Disease

Polycystic Kidney Disease is a kind of familial hereditary disease. So inheritance is the main cause of PKD.

Ⅰ. PKD is a hereditary disease. According to genetics, it can be divided into Autosomal Dominant Polycystic Kidney Disease (ADPKD) and Autosomal Recessive Polycystic Kidney Disease (ARPKD).

Firstly, ADPKD which belongs to autosomal dominant inheritance disease is common among PKD, with feature of familial aggregation. Both male and female can have equal incidence to get this disease, and this disease may be inherited for generations.

Secondly, ARPKD is also called infantile PKD which is not common among the disease of PKD. Most sick children die in a few months after birth. Only a few patients with lighter illness condition can survive from this disease to childhood, or even adult age.

Ⅱ. Symptoms of ADPKD usually appear when patients get to adult age, while obvious symptoms of ARPKD can be found in infantile stage. ADPKD is common among clinical cases, about 5% to 10% among end stage Kidney Disease. Main clinical symptoms of ADPKD are kidney enlargement, Haematuria, Albuminuria and High Blood Pressure, or even Renal Failure can be found in late stage of this disease.

Well then, what treatments are taken to treat PKD presently?

Firstly, operation: this treatment is not suggested to patients. Because after large cysts being removed, more space will be left for small cysts which can grow faster without pressure from large cysts. Repeated operation can cause serious injury to kidneys.

Traditional Chinese Medicine: through decocting, effective substances of Chinese Medicine can not be collected fully. Besides, after patients taken medicine, gastrointestinal digestion, whole body distribution and liver inactivation can all lead to a low medicine concentration at renal lesion, which can result in a slow effect, delaying illness condition treating.


Characteristic treatment of Chinese Medicine: Micro-Chinese Medicine solves the problem of stimulation on stomach and liver injury caused by oral medicine. During this treatment, medicine can effect on renal lesion directly which can offer a high medicine concentration at lesion. Through this way, cyst fluid can be absorbed more quickly and cysts can be reduced gradually, which can reduce pressure on kidney and relieve renal injury.

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