Operation can relieve pressure caused by big cysts on renal parenchyma and improve condition of renal ischemia and anoxia in a short time, which can reduce renal injury to a certain degree. However, operation still has some defects on treating PKD. Operation does not solve the root cause of PKD—cyst fluid secretion. Besides, operation can bring injury to kidneys when removing cysts. In addition, there are so many cysts in kidneys, and operation only deals with larger ones. So with large cysts removed, more space can be left for smaller cysts which grow more quickly without pressure from large cysts. Under such circumstance, these growing cysts can compress renal parenchyma again, causing kidney injury. What’s more, illness condition is easy to relapse and to develop into Renal Failure, or even Uremia.
Firstly, operation can only treat surface disease instead of treating real
disease cause. For this reason, it can not treat this disease completely. When
large cysts are removed, smaller cysts can grow rapidly without pressure from
these large cysts. And with illness condition worsening, a secondary operation
is needed, forming a vicious circle. Finally, kidney will be injured
Secondly, Kidney Transplant has not only high cost but also unpredictable
consequence. To most people, Kidney Transplant is a good way to treat PKD.
Actually, it is indeed. However, as a relative large operative trauma, Kidney
Transplant is a severe test to patients’ standing ability. Besides extremely
expensive cost and rare matched kidney, the probable rejection appeared after
operation may make some patients shrink back.