Traditionally, operations of Cyst Decortication and puncture sclerotherapy
are used to treat Polycystic Kidney Disease. Though these operations can reduce
cystic pressure on kidney and repair renal function in a short time, they can
not treat this disease completely. With big cysts being removed, their pressure
on small cysts is also reduced, which can make small cysts grow more rapidly.
After these small cysts growing bigger, they can compress kidney again and renal
function can be injured for a second time. Therefore, kidney can be injured by
cysts continuously and renal function injury can be worsening more
seriously.
Nephrectomy operation can be considered if PKD has involved bilateral kidneys
and the function of one kidney is normal. Furthermore, as for PKD patients,
Nephrectomy is not a good choice due to difficult post-operation care. Besides,
cysts can also relapse after operation.
During the treatment of Polycystic Kidney Disease, the basic method is to
improve blood circulation and permeability of cyst wall, which is beneficial to
recycle cyst fluid. With decreasing cyst fluid, cyst size become smaller and
pressure caused by cysts reduces. Through this way, pressure on healthy kidney
caused by cysts can be solved completely, and renal function can be recovered
gradually.
Theoretically, many treatment methods can be effective to treat PKD. But in
fact, there are so many difficulties in treating process. As a parenchymal
tissue, medicine is difficult to get into kidney. Kidney is different from
gastrointestinal system which can accept medicine directly. For this reason,
oral medicine only has a limited effect on kidney. Not only referring to PKD, in
the treatment of other Kidney Diseases, how to make medicine play their maximum
function is the most difficult problem.