Multiple Intracranial Aneurysm (MIA) which may gradually develop into rupture
and bleeding is rarely seen among Polycystic Kidney Disease patients.
Previously, the incidence of MIA is quite different to each report, which is
related with emphasis degree and examination methods. With the application of CT
technology, many smaller aneurysms with diameter less than 3mm are found.
According to the research of 266 Polycystic Kidney Disease patients, 8% patients
have MIA without any related symptoms, and 14% patients have intracranial
aneurysm with diameter more than 6mm. Rupture rate of intracranial aneurysm
among Polycystic Kidney Disease patients is not sure. It had been reported that
the incidence of it may be 1/2000 per year, and each patient who is older than
30 years old have an incidence of 1/1000 per year, with higher death rate than
End Stage Renal Failure patients caused by Polycystic Kidney Disease.
Intracranial Aneurysm should be treated in order to prevent a secondary
bleeding and cerebral ischemia. Both medicine and surgical operation can be
taken to treat intracranial aneurysm. As for patients who suffer from headache,
Codeine can be taken, but Aspirin is forbidden. More than 25% patients get
cerebral ischemia 5 to 14 days after aneurysm rupture. At this moment,
vasoactive drugs and calcium antagonist can be used properly. Surgical operation
should be taken as early as possible and 72 hours after bleeding is considered
as the best period, because nearly 35% patients may have the possibility to get
a secondary bleeding.