Besides cysts compressing and replacing healthy renal tissue, there are also
two factors can cause Polycystic Kidney Disease (PKD) to develop into Renal
Failure. One is ischemia, sclerosis or inflammation and fibrosis of non-cystic
tissue, including renal tubule, renal interstitium and blood vessel. The other
is high perfusion and high filtration of healthy nephron caused by progressive
renal function decline. All these factors can damage nephron further. From the
above, we can know that condition of surrounding region determines the
developing speed of renal function damage.
Besides, Hypertension and urinary tract infection is also a relevant factor
of affecting renal function decline. The period of Polycystic Kidney Disease
(PKD) developing into Uremia is some similar in one family. Some individual
cases may suffer from Renal Failure in young age, while some patients can keep a
good renal function until they are 80 years old. Generally, seldom renal
function decline happens before patients are 40 years old, and most patients can
keep half renal function when they are 70 years old. Male patients usually has a
worse prognosis than female, and patients who get this disease earlier also have
a worse prognosis than those who get this disease later. This period may be much
shorter if Polycystic Kidney Disease (PKD) patients suffer from Hypertension at
the same time. As for most patients, there is always concentrating functional
disorder of renal tubule before glomerular filtrating rate decrease.
In recent years, clinical doctors found that Micro-Chinese Medicine Osmotherapy can delay or even prevent the process of Polycystic Kidney Disease
(PKD) developing into Renal Failure. When PKD Uremia patients accept Western
Medicine Treatment, it can be effective to protect remained renal function and
recover injured tissue if patients take Micro-Chinese Medicine Osmotherapy at
the same time. Through this way, patients can live a normal life, even with
disease.
From the above, we can see that the period of Polycystic Kidney Disease (PKD)
developing into Renal Failure is not fixed. It is closely related with cyst
growing speed as well as complications and so on. Specialists on Polycystic
Kidney Disease (PKD) insist that besides factors mentioned above, treatment is
the main factor of affecting illness development. For this reason, patients
should accept proper treatment actively in order to prevent illness condition
aggravation.