2016年8月8日星期一

Renal Failure Caused by Polycystic Kidney Disease (PKD)

PKD is a kind of congenital Kidney Disease which involves bilateral kidneys. A large number of cysts with different sizes spread over the whole kidney, and some of them may open to each other. With cysts growing and increasing, they can enlarge kidney size and compress renal parenchyma, which causes renal parenchyma atrophy, resulting in renal function damage, or even Chronic Renal Failure finally.

PKD can be divided into two types. One is Infantile Type, referring to autosomal recessive inheritance. Most sick children die in several months after birth. The other one is Adult Type, referring to autosomal dominant inheritance. This type usually occurs at middle age, always complicated by polycystic lesions on liver, spleen, pancreas, ovary and bones as well as Intracranial Aneurysm.

As for the treatment of Renal Failure caused by Polycystic Kidney Disease, the key is to accept proper treatment and to prevent complications of Polycystic Kidney Disease actively in order to protect remained renal function and avoid further damage to renal function. As long as proper treatment can be taken in time, symptoms of most PKD patients can be relieved and renal function can be improved.


Hypertension, urinary tract infection and cysts rupture are common complications of Polycystic Kidney Disease. Meanwhile, these factors are also important factors that can induce and aggravate renal function damage. For this reason, these complications must be treated and controlled in time. Nephrotoxic medicine should be avoided during the treatment process. If patients get continuous Haematuria, or serious waist pain and abdominal pain, it mostly means cyst infection complicated with bleeding or cyst rupture. As this moment, patients should be sent to hospital for treatment as soon as possible so as not to worsen illness condition and aggravate Renal Failure.

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