Haematuria is a common complication among PKD patients. Most patients know that they are suffering from Polycystic Kidney Disease when they go to hospital for body check due to Haematuria. Almost all PKD patients have Haematuria. Well then, PKD patients may have the question that how does Haematuria occurs.
Due to renal microcirculation obstruction as well as renal ischemia and
anoxia, renal inherent cells can be injured, starting the process of Renal
Fibrosis which can worsen renal inherent cells injury contrarily. This can
reduce renal filtrating function. With renal filtrating function decline, kidney
can not prevent Red Blood Cells leakage. Then Haematuria occurs.
With patients aging, cysts keep growing and increasing, which can cause great
pressure on renal tissue and renal blood vessel, resulting in kidney local
microcirculation obstruction and then renal ischemia and anoxia. This can damage
endothelial cells of renal capillary, causing Haematuria leakage. Meanwhile,
filtration of inflammatory cells in blood can start the pathological process of
Renal Fibrosis. Renal function also declines progressively. Besides, some
patients may get Haematuria due to complicated urinary tract infection or Kidney
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