What Are the Early Symptoms of Purpura Nephritis
This question can be seen mainly from two aspects:
1. Renal surface manifestations: half of patients appear to have upper respiratory tract symptom before 1 to 3 weeks of the onset of the disease. Characteristic symmetry hemorrhagic rash can be found in almost all cases. It begins with urticaria-like and becomes punctuate purpura later which is higher than skin. What mentioned above is common in the lower limb extensor side and buttocks and rash repeat in several months.
60% of patients have abdominal pains and hematochezia; about 30% of them are accompanied by arthralgia, especially in knees and ankle knits. In some cases, renal damage is prior to rash. It isn’t obvious about the systemic manifestations, such as adult gastrointestinal symptom.
2. Renal damage manifestations: about 40% of patients have glomerulus damage, most of which present after 8 weeks of Purpura. It may attack two years later or before the existing of rash. Renal damage of anaphylactoid purpura is characterized by hematuria, accompanied by mild proteinuria.
What are the early symptoms of Purpura Nephritis? Clinical manifestations are as follows: 1. Acute Nephritis Syndrome: this is about 30%. 2. Accelerated Nephritis Syndrome: this is rarely seen. It can pause to renal failure and uremia from several weeks to several months. 3. Asymptomatic Hematuria and (or) Proteinuria Syndrome: this is about 50%. 4. Nephrotic Syndrome: adults account for 10% and this is can be seen more in children. 5. The disease may develop into Nephrotic Syndrome in some patients.