Renal Failure - What is Renal Failure
What is Renal Failure? High blood pressure, appearance of anemia or dark complexion, edema in facial region or lower limbs may be the symptoms of renal failure. Then what is Renal Failure?
Renal Failure can be divided into to acute and chronic types;
Acute Renal Failure: Patients’ condition of acute Renal Failure develops rapidly, which is caused by Renal blood supply (trauma or empyrosis), damaged kidney functions caused by some blocking factors or damaged by poison.
Chronic Renal Failure: Chronic Renal Failure is caused by long term renal lesions. Kidney functions decreases gradually as the time and disease develop.
What is Renal Failure?
There are various of causes of acute tubular necrosis. It can be summarized to two types:
1. Nephrotoxicity can cause acute tubular necrosis in certain conditions, such as sulfonamide, phenixin, mercurial, nol, daraprim in drugs and polymyxin, vancomycin, kanamycin, gentamicin, cephalosporin I, cephalosporin II, neomycin, amphotericin B in antibiotic, iodine contrast agent, Methoxyflurane anesthetic and biotoxin, such as venin, apisin, fish mushroomlike, Cantharidin, etc.
2. Acute Kidney tubules necrosis can be caused by severe Renal Ischemia, such as severe trauma, extensive burns, major surgery, massive haemorrhage, postpartum haemorrhage, severe infections, ichorrhemia, dehydration and electrolyte imbalance, especially for merger shock. In addition, hemoglobin released by intravascular hemolysis (such as blackwater fever, hemolysis caused by primaquine, favism, Incompatible blood transfusion, Oxidation arsenic poisoning, etc) and myohemoglobin caused by muscle mass trauma (such as squeeze, muscle inflammation) can damage kidney tubules to acute kidney tubules necrosis through renal excretion.