In most hospital, hormone therapy is the most common therapy for lupus nephritis. However, most people have found that their condition always relapse by using this therapy. Is hormone therapy useful for lupus nephritis?
Almost every patient with lupus (SLE) has kidney damage and about 60% of
patients have nephritis. Renal failure is the main cause of death for patients.
Lupus is a type of autoimmune disease which is featured with a disordered immune
Antibodies in the body do not only fight against foreign invaders but
also attack the body cells as well. So many immune complexes (the combination of
antibodies and antigens) are formed in the blood. When they deposit in the
kidneys, they will arouse an active immune reaction that will give a great
damage to kidney tissues.
Hormone therapy for lupus nephritis
Due to the active immune reaction, “little holes” will present in the kidney
tissues. So protein or blood cells will be leaked from the blood into the urine.
In this way, people will lose much protein, which will lead to many symptoms,
such as swelling or thrombus. Hormone therapy uses the feature of hormone to
block the “little holes” in order to reduce the protein loss. The proteinuria
can be removed only by using the hormone therapy. However, people cannot bear
the side effects of hormone drugs. So many people are seeking other therapy for
lupus nephritis after using hormone therapy for a long time.
Side effects of hormone therapy for lupus nephritis
Hormone drugs lead to disordered metabolism of water and other substances.
People would have swelling, high blood pressure, and glycosuria. Most of
patients have moon-face, thin skin, crinosity, acne, myasthenia and amyotrophy
Hormone therapy can trigger to have infections. Hormone restrains the immune
system to fight against virus or germs. So people will have serious infection
when they use hormone for a long time.
Osteoporosis will be formed by the hormone therapy. Rib and vertebra are the
main bone which is affected by hormone. It increases the metabolism of
phosphorus, so their bone is not as stiff as before.
Are you seeking a better therapy for lupus nephritis? You can consult our
experts online for more details about our individualized treatment which can
help you get a good curative effect with no hormone.