It is a major cause of ESRD for adults. FSGS can be seen in both children and adults. As the glomeruli (filters) in kidneys are sclerotic partially, the kidneys are not capable of functioning adequately, resulting in accumulation of metabolic wastes in blood. As a result, the creatinine level will be higher than normal. So, how to lower high creatinine level in FSGS effectively?
Keep a healthy diet
The creatinine is the end products of creatine in muscle. Too much consumption of meat can produce more creatinine in blood. Therefore, the patients should limit their daily intake of meat strictly.
Avoid strenuous exercise
Strenuous exercise can accelerate the metabolism of creatine in muscle thus producing more creatine in body. This will inevitably put much strain on kidneys when it is excreted by kidneys. So the patients with FSGS should avoid strenuous exercise and take part in aerobic exercise jogging, bicycling, swimming etc.
Immunotherapy
FSGS is a kind of autoimmune disorder, can remove creatinine and other metabolic wastes in blood thus lowering high creatinine in FSGS. As a result, the disease-fighting proteins called antibodies encounter and bind to antigens to form immune complexes in blood. When antigen-antibody complexes are deposited in the glomeruli, the body responds by mounting an inflammatory response to try to remove them. Ultimately, the inflammation can cause even more damage and impair the function of the glomeruli, leading to FSGS. Once the abnormal immune system is not corrected, it will cause frequent relapses of the disease. That is why Kidney Transplant fails in FSGS patients.
Immunotherapy is also known as biotherapy. It gas been found to be extremely effective. it can restore the impaired kidney tissues and recover the excretory function of the kidneys. Therefore, the patients with FSGS can get a fundamental recovery.