Patients with Nephrotic Syndrome who are resistant to the treatment or with
progressive forms of NS, such as Focal Segmental Glomerulosclerosis,
Membrano-proliferative disease, may suffer from potentially serious
complications.
Nephrotic Syndrome complications can be divided into two
categories: 1) acute complications associated with the nephrotic state,
expecially infections and thromboembolic disease; 2) long-term sequelae of
Nephrotic Syndrome, including effects on bones, growth, and the cardiovascular
system.
1. Infection
Severe infection, particularly cellulitis and spontaneous bacterial
peritonitis, can complicate NS. The rate of peritonitis is 2%~6%, and
overwhelming infection sill carries a mortality rate of 1.5%.
2. Thromboembolic complications
Patients with Nephrotic Syndrome are at significantly increased risk of
thrombosis. Report shows that the complication rates can be as high as 40% in
adults. The thrombosis risk is apparently lower in children, these events are
very severe. Patients with NS are in a hypercoagulable state, and arterial and
venous thrombi can develop in the major vessels. Sudden death can be caused by
massive pulmonary embolism.
3. Cardiovascular disease
Many factors increase the risk of cardiovascular disease in children with
Nephrotic Syndrome, including hyperlipidaemia, hypertension, hypercoagulability,
and anemia. Adults with Nephrotic Syndrome are related with an raised risk of
coronary heart disease.
Besides, patients may also suffer from other medical complications, such as
bone disease, drug toxic effects, hypothyroidism, and Acute Renal Failure.
Treatment of Nephrotic Syndrome is highly specialized in Shijiazhuang Kidney Disease Hospital, and we personalize your care include the most-advanced
immunotherapy with no side effects on your body.