Tripterygium Wilfordii Slows Down the Progression of Glomerulonephritis

Glomerulonephritis refers to the inflammation of glomeruli featured with proteinuria, hematuria etc. Some researches prove that tripterygium wilfordii has some effect in slowing the progression of glomeruli.
Tripterygium wilfordii is a kind of traditional Chinese medicine and has been used for centuries as an-inflammatory agent. It contains the active constituents which are diterpenoids like triptolide and tripdiolide, alkaloids etc. The diterpene triptolide is considered the major active component in tripterygium wilfordii.

Tripterygium wilfordii has an anti-inflammation function and plays the role of immunosuppressive drugs.
In Glomerulonephritis, the immune complexes in glomeruli can cause trigger an inflammation thus damaging the epithelial cells, mesangial cells etc. Tripterygium wilfordii can inhibit the abnormal inflammation and relive the damage to renal tissues and cells. Also, tripterygium wilfordii also can block the abnormal immune response and reduce the immune complexes formation to some extent.

In addition, tripterygium wilfordii can provide some effective ingredients which can promote the self-repairing of the epithelial cells. Therefore, it can reduce the leakage of protein to some extent.
As tripterygium wilfordii is a kind of natural herb medicine, it does not cause any adverse side effects to the patients with Glomerulonephritis.

Although tripterygium wilfordii has so many effects in the treatment of Glomerulonephritis, the patients can not get a good recovery just relying on this single herb medicine. In fact, in traditional Chinese medicine, every prescription is composed of four to sixty types of herb medicines. Those herb medicines are interacted and influenced to act and treat the disease from many aspects.

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Learn More: Micro-Chinese Medicine Osmotherapy Helps Treat Chronic Glomerulonephritis

How to Treat Immune Mediated Kidney Disease

Immune mediated kidney disease is caused by immune dysfunction or abnormality. Therefore, the key for treating this kind of kidney disease is to correct the immune system and suppress the abnormal immune response.

In healthy condition, immune system plays an important role in protecting our body from the foreign pathological substances. When opathogenic microorganisms invade into body, the immune system can activate the relative antibodies to kill them. Therefore, the human body can keep in a healthy state.

However, in some cases, the immune system performs abnormally and loses the protection function. The antibodies can not tell the foreign pathological substances and that of the body's own. As a result, the antibodies complexes or antigens and antibodies complexes may enter into glomeruli and deposit different parts of the glomeruli. Afterwards, the body tries to remove the immune complexes from body by mounting an inflammation. The immune complexes can impair the glomeruli and renal function thus leading to immune mediated kidney diseases. For different locations of the immune complexes, it presents different types of kidney diseases like IgA Nephropathy, Lupus Nephritis etc.

To correct the immune dysfunction and suppress the abnormal immune complexes, immunotherapy is recommended to the patients with immune mediated kidney disease.
Immunotherapy is not a single treatment method, but a complete treatment system and process.

In immunotherapy, blood purification can clear up the immune complexes associating in blood. In this way, it can prevent the further immune complexes in kidneys. However, blood purification can not remove the deposited immune complexes deposited in kidneys at all.

In immune regulation, Micro-Chinese Medicine Osmotherapy plays the main role in removing the deposited immune complexes. On one hand, it can degrade the immune complexes and improve blood circulation. Therefore, the degraded immune complexes will be excreted out of body finally through systemic circulatory system.

Immunotherapy treats immune mediated kidney disease from its root causes. Therefore, it can bring a favorable therapeutic effect for the patients.

What Are the Symptoms of Drug-induced Acute Interstitial Nephritis

Interstitial Nephritis refers to the inflammation of the space between tubules. If the patients are allergic to some drugs, it may lead to Acute Interstitial Nephritis, which is termed as Drug-induced Acute Interstitial Nephritis. The patients usually present the following symptoms:

▲ Hematuria is present in more than 90% cases of Drug-induced Acute Interstitial Nephritis. In about 80% cases, it is gross hematuria and was never associated with red blood cells casts.

▲ Pyuria nearly occurs in all cases of Drug-induced Acute Interstitial Nephritis complicated with leukocyte casts.

▲ More than 50% of adults and 15% of children may develop Renal Failure, in which about 20% is Oliguric Renal Failure. Approximately 33% of the patients developing Drug-induced Acute Interstitial Nephritis have renal function decline requiring dialysis.

▲ Fever is the most extrarenal symptom of the disease, which occurs in about 80% of patients. It can last several days after the discontinuation of drugs which causes Acute Interstitial Nephritis.

▲ A generalized cutaneous rash is observed in about 80% of the patients, and arthralgia is not common.

After the drug is discontinued, the relative symptoms like hematuria and pyuria can relieve within a few days. However, once Renal Failure occurs, it can last a long time and the patients need to receive effective treatment as early as possible.

Learn More: Which Acute Interstitial Nephritis Treatment Can Be Chose

What Are the Complications of Hypertensive Nephropathy

Hypertensive Nephropathy is a leading cause of End Stage Renal Failure. Uncontrolled, the renal injury can cause a series of complications. In return, the complications also can aggravate the disease progression. Therefore, it is very important to prevent the incidence of complication to slow down the progression of Hypertensive Nephropathy. The common complications of Hypertensive Nephropathy are as follows:

1. Glomerulosclerosis and Chronic Renal Failure
If the patients have a poor control of blood pressure over time, it can trigger glomerular ultrafiltration which can lead to glomerulosclerosis. In turn, for renal injury, the kidneys can not secrete hormone renin in charge of regulating blood pressure. As a result, the blood pressure is elevated thus accelerating Hypertensive Nephropathy progression.

2. Cerebrovascular accident
Cerebrovascular accident is a serious complication in Hypertensive Nephropathy with high morbidity. It can lead to disability and even death to the patients. The morbidity of cerebrovascular accident rises with blood pressure. Therefore, the patients should take effective preventive measures to avoid the damage. If they have fatigue, nausea, vomiting, dizziness etc for no clear reasons, they should go to see a doctor immediately.

3. Increased urination at night
In the early stage of Hypertensive Nephropathy, the renal tubule is impaired seriously. As a result, the concentration of urine declines, which can cause frequent urination at night.

4. Swelling
Swelling mainly occurs around eyelids and lower limbs and other loose body part. It is obviously serious in the morning. After activity, it may relieve and even disappear.

5. Protein in urine
The patients with Hypertensive Nephropathy usually have mild proteinuria and microscopic hematuria and urine cast.
The complications of Hypertensive Nephropathy can accelerate the disease progression into Renal Failure. Therefore, the patients should not take proper treatment to stop the disease aggravation as early as possible.

Learn More: Help Prevent Hypertensive Nephropathy from Developing Renal Failure

What Is Interstitial Nephritis:Causes,Symptoms and Treatment

Interstitial Nephritis also known as Tubulointerstitial Nephritis refers to the inflammation of the space between the renal tubules. The inflammation can impair the kidneys leading renal function decline.

Causes of Interstitial Nephritis
l Interstitial Nephritis includes Chronic Interstitial Nephritis and Acute Interstitial Nephritis. Allergic reaction to a drug is a common cause of Acute Interstitial Nephritis.
l Autoimmune disorders like systemic lupus erythematosus can cause immune complexes deposit in the renal tubules which cause tubule interstitium injury resulting in Interstitial Nephritis.
l Too little potassium and much calcium or uric acid in blood also can cause Interstitial Nephritis.
l Side effects of medications like thiazide diuretics and certain antibiotics such as penicillin, methicillin etc.

Symptoms of Interstitial Nephritis
l In severe case, the patients with Interstitial Nephritis may experience Acute Renal Failure.
l Blood and protein in urine
l Increased or decreased urine output
l Swelling, especially in the part of loose tissues
l Weight gain from retention of fluid
l In some cases of Interstitial Nephritis, some patients may have rash.

Treatment of Interstitial Nephritis
The patients should choose effective treatment depending on the cause of the kidney problems. If Interstitial Nephritis is associated with medications, avoiding using them can relieve the symptoms quickly.
They also can manage their diet and limit the salt and protein intake. It also can delay the disease progression.

If Interstitial Nephritis is caused by autoimmune disorder, the patients should take effective treatment to correct the abnormal immune system, clear up the immune complexes as well as remove the deposited immune complexes in renal tubule. Once the inflammation is eliminated, it is possible to stop the damage to kidneys.

If you or your loved one is Interstitial Nephritis suffer and wants to know more information about other aspects of the disease, you can leave a message below or consult us on line.

Is Acupuncture Helpful for Relieving Pain in PKD

Acupuncture is a complex therapeutic system in traditional Chinese medicine (TCM). It has been used to treat a variety of diseases. Some researches prove that acupuncture is helpful for relieving pain in Polycystic Kidney Disease (PKD).

Acupuncture is originated from ancient China. Usually, it is used as an assistant treatment of Chinese herb medicines in treating disease. The acupuncture is inserted into specific acupuncture points. When the points are stimulated, beneficial physical and mental changes occur.

Acupuncture achieves the goal of relieving pain in Polycystic Kidney Disease by two ways. The hormone endorphin is a kind of natural pain killer in our body. The acupuncture can stimulate related point to promote the releasing of the hormone. As more endorphin is released, it can relieve the pain to some extent. Moreover, acupuncture can work on nerve system and prevent the pain signals from transmitting to the brain.

Although acupuncture can relieve pain in PKD temporarily, it can not treat the pain from the underlying cause. PKD is featured by numerous cysts on kidneys. With age, the cysts increase in size and number. The enlarged cysts oppress the normal nephrons thus leading to back or abdominal pain. If the cysts rupture, the patients may experience intense pain suddenly.

Therefore, the key to eliminating pain in PKD is to stop the cysts enlargement and shrinking the enlarged ones. The traditional Chinese medicine need to intervene in the treatment of PKD.

On one hand, traditional Chinese medicine can dilate renal arteries. It can improve the blood and oxgen supply to kidneys so as to relieving renal ischemia and anoxia. Therefore, it can stop the renal fibrosis.
On the other hand, it can transfer the function of lining cells on cyst wall and boost the reabsorption of cystic fluid. Therefore, the cysts will shrink gradually.

Therefore, once the oppression to the kidneys eliminates the pain in PKD will also disappear afterwards.

Learn More: Polycystic Kidney Disease Treatment in China

Traditional Chinese Medicine (TCM) for Chronic Renal Failure

Traditional Chinese medicine (TCM) is a complete medicine system in China with thousands of years’ history. At present, more and more medical experts find the efficiency of TCM and introduce it into the treatment of Chronic Renal Failure. The following herbs are often used in the treatment of Chronic Renal Failure.

Astragalus membranaceus( Huangqi)
The active components are flavonoids, polysaccharides, triterpene, glycosides, saponins and amino acids. Astragalus membranaceus is used in clinic for its effect on cytokines on reactive oxgen species, ischemia and mechanisms of renal fibrosis. Once the renal ischemia improves and the renal fibrosis is inhibited, it can slow down the progression of Chronic Renal Failure effectively.

Angelica sinensis (Dang gui)
Angelica sinensis is indigenous to China. It has anticoagulant effects. It can prevent the formation of thrombus and improve blood circulation. Therefore, it can increase the blood supply to kidneys.

Tripterygium wilfordii (Lei Gong Teng)
It has been explored for anti-inflammatory and immunosuppressant activities. The active component triptolide in tripterygium wilfordii can reduce the inflammation of kidneys thus reducing the renal damage and delaying the arrival of Chronic Renal Failure.

Rhubarb (Dahuang)
Rhubarb has an obvious effect in improving renal function and reducing protein in urine and glomerular scarring. Also Rhubarb-tannins can reduce uremic toxins in blood and improve glomerular filtration rate. The component rhein can attenuate hypertrophy of renal tubular epithelial cells and accumulation of extracellular matrix. Therefore, it can effectively reduce glomerular damage and improve renal function to some extent thus delaying the progression of Chronic Renal Failure.

Ligusticum wallichii (Chuanxiong)
Ligusticum wallichii is used for the treatment of ischemia and thrombosis. It can slow down and even halt the progression of Chronic Renal Failure. The effective component ferulic acid in ligusticum wallichii can reduce proteinuria and improve renal function by correcting blood system disorder.
The above article has introduced the common traditional Chinese medicines used in the treatment of Chronic Renal Failure. However, you should know that every prescription of disease is composed of several kinds of herbs in certain dosages. Therefore, you should not use Chinese herbs without a permission of a professional physician.

If you want to know the prescription of Chronic Renal Failure based on your illness condition, you can leave a message below or consult us on line.

Learn More: Chinese Medicines for Chronic Renal Failure Patients