Urinary Tract Infection Caused by Polycystic Kidney Disease

Urinary tract infection is a common complication of Polycystic Kidney Disease which includes cystitis, pyelonephritis, cysts infection and perinephric abscess. The primary clinical manifestation is urinary tract infection for about 20% patients with Polycystic Kidney Disease. 50%-70% patients with Polycystic Kidney Disease will present urinary tract infection at least once and the females are more common to present it. It is very difficult to be cured and most of them will develop into perinephric abscess and sepsis. About 1/3 patients with Polycystic Kidney Disease who are under dialysis have the symptom of urinary tract infection. Although they are taking effective antibiotics to prolong the course of treatment, there are still some patients develop into perinephric abscess.

The clinical manifestation and imaging study

When Polycystic Kidney Disease is accompanied with cystitis, the clinical manifestations can be presented as urgent urination, odynuria and pain in bow area. If the infection occurs in urinary tract, the persistent fever and backache may appear. Clinically, it is difficult to differ pyelonephritis from cysts infection. If the urine culture presents to be positive, there is an increase of white blood cells in blood, and reacts quickly to common anti-infection therapy. While, if the blood culture presents to be positive and there is pressing pain in the local area, the cysts might be infected.

When patients with Polycystic Kidney Disease seem to have urinary tract infection, they should take examinations of imaging study and abdominal plain film (AP), through which the location, size, number of urolithiasis and perinephric can be seen. CT scan has a good sensitivity to perinephric abscess, while for those who have get urinary tract infection; the equipment inspection may increase the risk of getting sepsis. Therefore, the retrograde pyelography should be avoided if possible.

Treatment


Shijiazhuang Kidney Disease Hospital adopts the Micro-Chinese Medicine Osmotherapy to treat urinary tract infection, which has achieved remarkable efficacy. It can inactivate the inflammation caused by infection; inhibit the growth of the kidney cysts; repaired the damaged kidney function.

Are Dialysis and Surgeries the best Therapies for Polycystic Kidney Disease

Polycystic Kidney Disease(PKD) is a genetic kidney disease which exists from birth. However, When cysts are small, it is not easy to test out this disease. After that, cysts will keep on growing and related symptoms such as waist pain, proteinuria, hematuria and blood pressure increase appear, which indicate that the cysts grow to a certain degree. But patients are rather passive since no effective treatment is suggested to take for them but to deal with the symptoms such as high blood pressure. Mostly they may wait for the cysts to grow big enough to take surgeries or renal supplant treatment such as dialysis. However, can kidney replacement supplant and surgeries treat the disease fundamentally?

Surgeries mainly include pumping liquid solidification surgery and decortication surgery. Both of the surgeries can help to relieve the pressure of the cysts on the renal parenchyma and save the remaining nephrons from further pressing and damage, for which it can improve the ischemia and hypoxia state, recover certain kidney functions and prolong the development of the disease. However, the cysts in the deep of the kidneys are hard to be eliminated and the surgeries may bring certain new traumas, so the cysts may recur in later times and kidney functions will still be damaged. Moreover, at the end stage kidney failure, the decompression treatment will be meaningless for the surgeries may add the severity of the disease.

For patients with rather high creatinine level, dialysis can help to reduce the level of creatinine in a short time, for which the life of the patients can be prolonged. However, simple use of dialysis can only reduce creatinine ostensibly, but it can only relieve the condition temporarily and kidney functions can't be recovered. Therefore the roots of the disease can't be treated. Then is there any better treatment for Polycystic Kidney Disease?

Micro-Chinese Medicine Osmotherapy, characteristic therapy in Shijiazhuang Kidney Disease Hospital, can function to treat the disease through the following aspects:

1. Activate blood and dredge collaterals, strengthen the blood circulation and the permeability on cystic walls, and improve the reabsorption of cystic liquid.
2. Inhibit the secreting function of the cells on cystic walls and decrease the secretion of cystic liquid.

3. Recover kidney damages caused by the cysts.


As can be seen, Micro-Chinese Medicine Osmotherapy can imorove the environment inside within the body by dispelling stasis and scavenging, which makes a good preparation for Immunotherapy—a natural therapy by taking advantage of the strong self-renewal, regenerating and differentiating abilities of the Immunotherapy to treat the disease. The illness condition can really be improved a lot by the combination of the two therapies. And in clinical practice, they have shown their strong treatment effects of treating Polycystic Kidney Disease in many cases.

Unveil the Mysterious Relationship between Polycystic Kidney Disease and High Blood Pressure

Many people have knowledge that high blood pressure can lead to Coronary Heart Disease and Stroke, while, few people know how it is related with Polycystic Kidney Disease. As a result, patients with Polycystic Kidney Disease do not pay much attention to when they present high blood pressure.

The continuous growth of the cysts will press on the normal kidney tissues, which will lead to ischemia and anemia of the kidneys. At this time, the kidneys will secrete more renins; blood vessels will secret more angiotensin so the blood vessels will contract; finally the blood pressure will increase.

Once blood pressure increases, it will in turn aggravate the function of kidneys, thus forming a vicious circle between high blood pressure and kidney function. If patients have a high blood pressure for a long time, the kidney capillaries will be affected first. The kidney intrinsic cells will be damaged then.

If patients can not control their high blood pressure, pathological changes in the kidneys will be severer. Some patients might progress into Chronic Renal Failure or Uremia.

Therefore, Polycystic Kidney Disease patients with high blood pressure should have routine check, which includes urine routine, blood routine and kidney functions. What is more, patients should pay attention to their daily diet.

1. Patients with high blood pressure should arrange their diet properly. Do not eat too full. The dinner should be light.

2. The intake of the salt should be controlled in 2-5g per day.

3. Foods that contain potassium can resist the damage of the vessels caused by high blood pressure which should be taken regularly. The potassium can be found from beans, potatoes, fish etc.


4. Fresh vegetables and fruits should be taken everyday because they contain mass Vitamin B and Vitamin C.

Treat Proteinuria(protein in urine) of Polycystic Kidney Disease with Micro-Chinese Medicine Osmotherapy

Polycystic Kidney Disease is a genetic disorder where numerous fluid-filled cysts are formed in the kidneys. Many Polycystic Kidney Disease patients are very scared when they present proteinuria( protein in urine). The continuous enlargement of the cysts will press the kidney issues, especially the kidney tubules and kidney capsules. The occurrence of protein in urine is usually caused by the damage of the reabsorption function of the tubules. When the glomeruli are damaged greatly, mass proteinuria (protein in urine) will present.

If patients with Polycystic Kidney Disease can not control their proteinuria, large amount of protein can lead to the damage of kidneys. As time goes on, kidney failure is likely to happen, which will be very difficult to be dealt with.

So, patients with Polycystic Kidney Disease should take regular check of urine to see whether proteinuria occurs. The common test can be Albumin-to-Creatinine Ratio (UACR) test. For a normal person, UACR is not more than 30mg/g. If it is more, patients should take a second test.

However, if you present proteinuria, you should not be scared. What you should do is to seek medical help positively. If the proteinuria is not well controlled, Polycystic Kidney Disease and Kidney functions will be aggravated further.

Experts from Shijiazhuang Kidney Disease Hospital recommend the Micro-Chinese Medicine to treat proteinuria caused by Polycystic Kidney Disease. Because the proteinuria is caused by the damage of renal tubules, the treatment should start from the repair of the tubules.

The damage of kidney tubules is caused by the pressure caused by the cysts. So the shrink of the cysts is necessary. The Micro-Chinese Medicines can be permeated into the kidneys directly with the facilities of permeation. They can inactivate the epithelial cells of the cells, which would not be secreting cyst fluid anymore. What is more, the active substances of the Micro-Chinese Medicine have the function of dilating blood vessels so that the enough blood and oxygen can be provided to the kidneys. At last, the Micro-Chinese medicines can provide much nutritious substance such as Vitamin, microelements, organic acids, etc for the repair of the kidney intrinsic cells. Finally, when the damaged kidney intrinsic cells including glomeruli and tubules and they all back to work normally, the protein in the blood can not be filtered out. Then the proteinuria is effectively controlled.


From the above introduction, we can see how Micro-Chinese Medicine Osmotherapy works in controlling proteinuria. If you have any questions about your illness condition, please send email to kidney-treatment@hotmail.com or just consult our online experts. It is our great pleasure if we can help.

Can Polycystic Kidney Disease Patients Give Birth to a Healthy Baby

Polycystic Kidney Disease belongs to hereditary diseases where numerous cysts are formed in both of the kidneys. If one parent has this disease, his or her children have a 50% chance to get it. Many patients with Polycystic Kidney Disease who are newly married are wondering whether they can give birth to a healthy baby. Actually, they can be pregnant when their illness conditions are under control.

The new married couples should pay attention to the following points when they are going to have a baby.

1. Have routine checks about their illness condition.

B-ultrasound is the primary method to check Polycystic Kidney Disease before they deliver a baby. When they are pregnant for about 12 weeks, the B-ultrasound can present the babies’ kidney structures through vagina. They can have check every 2-4 weeks to diagnose the changes in the both kidneys so that the changes can be found timely.

2. It is more exact if diagnosing it with genes diagnosis.

It is a breakthrough in diagnosing pathological changes before they are pregnant for 2-4weeks. To have locus linkage analysis through chorion, amniocentesis, cord blood etc. Or they can take antenatal diagnosis such as genic mutation at certain positions. When abnormality is found through the following methods, they can make an end to gestation at a proper time.

3. The babies should have routine check about every half a year to make sure they are safe.

Experts here remind that patients should not take it for granted that their babies will not have Polycystic Kidney Disease since they did not present abnormality.


From the above, we can see that even if patients have Polycystic Kidney Disease, they can have a healthy baby.

Dietotherapy Plays an Important Role in Slowing down Renal Failure Caused by PKD

Polycystic Kidney Disease (PKD) is a genetic disease and can accompany patients’ whole life. If the patients do not receive effective treatment in an early time, all of them will end with Renal Failure. In order to slow down Renal Failure, dietotherapy plays an important role on this point. Moreover, dietotherapy can alleviate the complications of Renal Failure.

Dietotherapy for patients with Renal Failure before dialysis

(1) Protein intake

At the first and second stages of Renal Failure, the patients should reduce their protein intake to 0.8 grams/kg per day. After their disease develops into the third stage of Renal Failure, they should keep a low-protein diet and keep their protein intake within 0.6 grams/kg per day. In their total protein intake, haft of the protein should be obtained from quality protein such as lean meat, fish, and egg white and so on.

(2) Calorie intake

When patients keep a low protein diet, they should have enough calorie intakes so as to guarantee enough nutrition. They should have 125~146 calories/kg per day.

(3) Other nutrition

The patients should be supplied with various kinds of vitamins and folic acid. However, when patients have hyperphosphatemia , they should keep the phosphorus intake below 800 milligrams per day.

However, the patient with Renal Failure should make their diet schedule under their doctors’ guidance. Some patients think that protein can accelerate the kidney damage so they limit their protein intake blindly. As a result, it causes severe malnutrition to them so the patients are very likely to have fatigue, anemia and so on. Therefore, for patients with Renal Failure, if they keep a low-protein diet, they should have follow-up regally and adjust their dietary schedule based on their disease condition.

The doctors should help patients with Renal Failure make a scientific diet schedule according to different patients’ kidney condition, pathogenesis ( such as Diabetic Nephropathy, Hypertensive Nephropathy, Chronic Nephritis and so on), nutrition condition, absorption and digestion and so on).


Scientific dietotherapy is important for patients with Renal Failure to slow down their kidney damage, Therefore, they should make a proper dietary schedule under their doctors’ guidance.

Can Serum Creatinine Level Reflect Renal Function Accurately

Polycystic Kidney Disease (PKD) is a chronic genetic disease. As the cysts enlarge with age, they will oppress the neighboring kidney tissues thus causing Renal Failure. As kidney has strong sufficient compensatory capacity, the patients do not have symptoms in the early time. Many patients think that if their serum creatinine keeps in the normal range, their renal function must be also normal. In fact, this idea is wrong. Although serum creatinine can reflect the kidney capacity in excreting metabolic wastes and toxins, but it is not sensitive. Only when more than half of patients’ renal function is lost, will the serum level exceed the normal level. The patients with Renal Failure can know their renal function better by the following formula.

Creatinine clearance rate= (140-Age)* body weight (kilogram)*88.4/72*serum creatinine level (umol/L)

If you are women patients, after you get the above result, you should use it to multiply 0.85 then you can get your creatinine clearance rate.

The normal creatinine clearance rate should keep within 80~120 ml/minute. The lower your creatinine clearance rate is, the worse your renal function is.

If your creatinine clearance rate is between 10~15ml/minute, usually your disease has developed into End Stage Renal Failure. It is not proper for patients with Renal Failure to judge their renal function just from their creatinine level. For example, if the two patients have the same creatinine level: 95umol/L, but other factors are different.

Women patient: 75 years old; 50kilogams

Man patient: 25 years old; 75kilogrmas

From the above formula, we can see that the former patients’ creatinine clearance rate is 36umol/L and the latter is 111umol/L. Although the former patient’ renal function has been damaged seriously, but the creatinine level does not reflect it accurately.


Therefore, the patients with Renal Failure should not judge their renal function from their creatinine level simply. They should take other indexes in consideration comprehensively so as to receive effective treatment in the fist time.